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Cajun Chicken Alfredo Pasta garnished with parsley on a white plate

Cajun Chicken Alfredo Pasta

A delightful fusion of rich, creamy flavors and a kick of spice, this Cajun Chicken Alfredo Pasta is a comforting, satisfying meal perfect for family dinners or special occasions.
Prep Time 15 minutes
Cook Time 25 minutes
Total Time 40 minutes
Course Dinner, Main Course
Cuisine American, Cajun
Servings 4 servings
Calories 600 kcal

Ingredients
  

For the Cajun Chicken

  • 2 pieces boneless, skinless chicken breasts (about 1 pound)
  • 2 tablespoons Cajun seasoning
  • 1 tablespoon olive oil
  • Salt and pepper to taste

For the Alfredo Sauce

  • 1 cup heavy cream
  • 1/2 cup grated Parmesan cheese
  • 2 tablespoons unsalted butter
  • 2 cloves garlic, minced
  • Salt and pepper to taste
  • 1/4 teaspoon nutmeg (optional)

For the Pasta

  • 8 ounces fettuccine or your favorite pasta
  • Fresh parsley, chopped, for garnish

Instructions
 

Cook the Pasta

  • Bring a large pot of salted water to a boil. Add the fettuccine and cook according to package instructions until al dente, typically 8–10 minutes. Drain the pasta, reserving 1/2 cup of the pasta water.

Prepare the Cajun Chicken

  • While the pasta is cooking, season both sides of the chicken breasts with Cajun seasoning, salt, and pepper.

Cook the Chicken

  • Heat olive oil in a large skillet over medium-high heat. Add the seasoned chicken breasts and cook for about 5–7 minutes on each side until golden brown and cooked through (internal temperature should reach 165°F). Remove from skillet and let rest before slicing.

Make the Alfredo Sauce

  • In the same skillet, reduce heat to medium and add butter and minced garlic. Sauté until fragrant, about 1 minute.
  • Pour in the heavy cream, stirring continuously, and let it simmer for 2–3 minutes to thicken slightly.

Incorporate Parmesan

  • Add grated Parmesan cheese to the cream mixture, stirring until melted and smooth. Season with salt, pepper, and nutmeg (if using) to taste.

Combine Pasta and Sauce

  • Add the drained pasta to the skillet with the sauce, tossing to coat. If the sauce is too thick, add a splash of reserved pasta water for desired consistency.

Add Chicken

  • Gently mix in the sliced Cajun chicken, tasting and adjusting seasoning as needed.

Serve

  • Divide the Cajun Chicken Alfredo Pasta among serving plates, garnish with fresh parsley, and serve immediately.

Notes

For an even more authentic flavor, consider making your own Cajun seasoning. You can also substitute heavy cream with half-and-half or plant-based milk for a lighter version.
Keyword Cajun Chicken Alfredo, Comfort Food, Creamy Pasta, Pasta Recipe, Spicy Chicken